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Mechanistic Studies of Fatty Acid Activation by CYP152 Peroxygenases Reveal Unexpected Desaturase Activity

[Image: see text] The majority of cytochrome P450 enzymes (CYPs) predominantly operate as monooxygenases, but recently a class of P450 enzymes was discovered, that can act as peroxygenases (CYP152). These enzymes convert fatty acids through oxidative decarboxylation, yielding terminal alkenes, and t...

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Detalles Bibliográficos
Autores principales: Pickl, Mathias, Kurakin, Sara, Cantú Reinhard, Fabián G., Schmid, Philipp, Pöcheim, Alexander, Winkler, Christoph K., Kroutil, Wolfgang, de Visser, Sam P., Faber, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323616/
https://www.ncbi.nlm.nih.gov/pubmed/30637174
http://dx.doi.org/10.1021/acscatal.8b03733