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The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: insights into cancer resistance mechanisms

BACKGROUND: Spalax, the blind mole rat, developed an extraordinary cancer resistance during 40 million years of evolution in a subterranean, hypoxic, thus DNA damaging, habitat. In 50 years of Spalax research, no spontaneous cancer development has been observed. The mechanisms underlying this resist...

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Detalles Bibliográficos
Autores principales: Altwasser, Robert, Paz, Arnon, Korol, Abraham, Manov, Irena, Avivi, Aaron, Shams, Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323709/
https://www.ncbi.nlm.nih.gov/pubmed/30621584
http://dx.doi.org/10.1186/s12864-018-5417-z