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Rapid fine mapping of causative mutations from sets of unordered, contig-sized fragments of genome sequence

BACKGROUND: Traditional Map based Cloning approaches, used for the identification of desirable alleles, are extremely labour intensive and years can elapse between the mutagenesis and the detection of the polymorphism. High throughput sequencing based Mapping-by-sequencing approach requires an order...

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Detalles Bibliográficos
Autores principales: Rallapalli, Ghanasyam, Corredor-Moreno, Pilar, Chalstrey, Edward, Page, Martin, MacLean, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323790/
https://www.ncbi.nlm.nih.gov/pubmed/30616525
http://dx.doi.org/10.1186/s12859-018-2515-5