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Rapid fine mapping of causative mutations from sets of unordered, contig-sized fragments of genome sequence
BACKGROUND: Traditional Map based Cloning approaches, used for the identification of desirable alleles, are extremely labour intensive and years can elapse between the mutagenesis and the detection of the polymorphism. High throughput sequencing based Mapping-by-sequencing approach requires an order...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323790/ https://www.ncbi.nlm.nih.gov/pubmed/30616525 http://dx.doi.org/10.1186/s12859-018-2515-5 |