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Shikonin inhibits cancer cell cycling by targeting Cdc25s

BACKGROUND: Shikonin, a natural naphthoquinone, is abundant in Chinese herb medicine Zicao (purple gromwell) and has a wide range of biological activities, especially for cancer. Shikonin and its analogues have been reported to induce cell-cycle arrest, but target information is still unclear. We hy...

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Detalles Bibliográficos
Autores principales: Zhang, Shoude, Gao, Qiang, Li, Wei, Zhu, Luwei, Shang, Qianhan, Feng, Shuo, Jia, Junmei, Jia, Qiangqiang, Shen, Shuo, Su, Zhanhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323793/
https://www.ncbi.nlm.nih.gov/pubmed/30616572
http://dx.doi.org/10.1186/s12885-018-5220-x