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Shikonin inhibits cancer cell cycling by targeting Cdc25s
BACKGROUND: Shikonin, a natural naphthoquinone, is abundant in Chinese herb medicine Zicao (purple gromwell) and has a wide range of biological activities, especially for cancer. Shikonin and its analogues have been reported to induce cell-cycle arrest, but target information is still unclear. We hy...
Autores principales: | Zhang, Shoude, Gao, Qiang, Li, Wei, Zhu, Luwei, Shang, Qianhan, Feng, Shuo, Jia, Junmei, Jia, Qiangqiang, Shen, Shuo, Su, Zhanhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323793/ https://www.ncbi.nlm.nih.gov/pubmed/30616572 http://dx.doi.org/10.1186/s12885-018-5220-x |
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