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Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis

OBJECTIVE: The objective was to determine if dose reduction is non-inferior to full-dose TNFi to maintain low disease activity (LDA) in patients already in remission with TNFi, in axial spondyloarthritis. METHODS: Randomized, parallel, non-inferiority, open-label multicentre clinical trial. Patients...

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Detalles Bibliográficos
Autores principales: Gratacós, Jordi, Pontes, Caridad, Juanola, Xavier, Sanz, Jesús, Torres, Ferran, Avendaño, Cristina, Vallano, Antoni, Calvo, Gonzalo, de Miguel, Eugenio, Sanmartí, Raimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323809/
https://www.ncbi.nlm.nih.gov/pubmed/30621746
http://dx.doi.org/10.1186/s13075-018-1772-z