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Multiple amino acid substitutions involved in the adaption of three avian-origin H7N9 influenza viruses in mice

BACKGROUND: Avian influenza A H7N9 virus has caused five outbreak waves of human infections in China since 2013 and posed a dual challenge to public health and poultry industry. The number of reported H7N9 virus human cases confirmed by laboratory has surpassed that of H5N1 virus. However, the mecha...

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Detalles Bibliográficos
Autores principales: Qin, Jianru, Peng, Ouyang, Shen, Xiaoting, Gong, Lang, Xue, Chunyi, Cao, Yongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323857/
https://www.ncbi.nlm.nih.gov/pubmed/30621708
http://dx.doi.org/10.1186/s12985-018-1109-1