A statistical measure for the skewness of X chromosome inactivation based on case-control design

BACKGROUND: Skewed X chromosome inactivation (XCI), which is a non-random process, is frequently observed in both healthy and affected females. Furthermore, skewed XCI has been reported to be related to many X-linked diseases. However, no statistical method is available in the literature to measure...

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Detalles Bibliográficos
Autores principales: Wang, Peng, Zhang, Yu, Wang, Bei-Qi, Li, Jian-Long, Wang, Yi-Xin, Pan, Dongdong, Wu, Xian-Bo, Fung, Wing Kam, Zhou, Ji-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323862/
https://www.ncbi.nlm.nih.gov/pubmed/30616589
http://dx.doi.org/10.1186/s12859-018-2587-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323862/
https://www.ncbi.nlm.nih.gov/pubmed/30616589
http://dx.doi.org/10.1186/s12859-018-2587-2

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