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A statistical measure for the skewness of X chromosome inactivation based on case-control design
BACKGROUND: Skewed X chromosome inactivation (XCI), which is a non-random process, is frequently observed in both healthy and affected females. Furthermore, skewed XCI has been reported to be related to many X-linked diseases. However, no statistical method is available in the literature to measure...
Autores principales: | Wang, Peng, Zhang, Yu, Wang, Bei-Qi, Li, Jian-Long, Wang, Yi-Xin, Pan, Dongdong, Wu, Xian-Bo, Fung, Wing Kam, Zhou, Ji-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323862/ https://www.ncbi.nlm.nih.gov/pubmed/30616589 http://dx.doi.org/10.1186/s12859-018-2587-2 |
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