CADD: predicting the deleteriousness of variants throughout the human genome

Combined Annotation-Dependent Depletion (CADD) is a widely used measure of variant deleteriousness that can effectively prioritize causal variants in genetic analyses, particularly highly penetrant contributors to severe Mendelian disorders. CADD is an integrative annotation built from more than 60...

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Detalles Bibliográficos
Autores principales: Rentzsch, Philipp, Witten, Daniela, Cooper, Gregory M, Shendure, Jay, Kircher, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323892/
https://www.ncbi.nlm.nih.gov/pubmed/30371827
http://dx.doi.org/10.1093/nar/gky1016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323892/
https://www.ncbi.nlm.nih.gov/pubmed/30371827
http://dx.doi.org/10.1093/nar/gky1016

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