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KinaMetrix: a web resource to investigate kinase conformations and inhibitor space

Protein kinases are among the most explored protein drug targets. Visualization of kinase conformations is critical for understanding structure–function relationship in this family and for developing chemically unique, conformation-specific small molecule drugs. We have developed Kinformation, a ran...

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Detalles Bibliográficos
Autores principales: Rahman, Rayees, Ung, Peter Man-Un, Schlessinger, Avner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323924/
https://www.ncbi.nlm.nih.gov/pubmed/30321373
http://dx.doi.org/10.1093/nar/gky916