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Pancan-meQTL: a database to systematically evaluate the effects of genetic variants on methylation in human cancer
DNA methylation is an important epigenetic mechanism for regulating gene expression. Aberrant DNA methylation has been observed in various human diseases, including cancer. Single-nucleotide polymorphisms can contribute to tumor initiation, progression and prognosis by influencing DNA methylation, a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323988/ https://www.ncbi.nlm.nih.gov/pubmed/30203047 http://dx.doi.org/10.1093/nar/gky814 |