Efficacy of Dual Inhibition of Glycolysis and Glutaminolysis for Therapy of Renal Lesions in Tsc2(+/−) Mice()

Tuberous sclerosis is caused by mutations in the TSC1 or TSC2 gene and characterized by development of tumors in multiple organs including the kidneys. TSC-associated tumors exhibit somatic loss of the second allele of the TSC genes, leading to aberrant activation of the mechanistic target of rapamy...

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Detalles Bibliográficos
Autores principales: Jones, Ashley T., Narov, Kalin, Yang, Jian, Sampson, Julian R., Shen, Ming Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324218/
https://www.ncbi.nlm.nih.gov/pubmed/30622053
http://dx.doi.org/10.1016/j.neo.2018.12.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324218/
https://www.ncbi.nlm.nih.gov/pubmed/30622053
http://dx.doi.org/10.1016/j.neo.2018.12.003

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