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Ameliorative Effect of Gallic Acid on Methotrexate-Induced Hepatotoxicity and Nephrotoxicity in Rat

We investigated the protective effect of gallic acid (GA) against methotrexate (MTX)-induced hepatotoxicity and nephrotoxicity. Male Wistar rats were randomized into five groups (n = 6/group): I, control; II, MTX-treated for seven days; III, pre-treated with GA for seven days, followed by MTX for se...

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Detalles Bibliográficos
Autores principales: Olayinka, Ebenezer Tunde, Ore, Ayokanmi, Adeyemo, Oluwatobi Adewumi, Ola, Olaniyi Solomon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324488/
https://www.ncbi.nlm.nih.gov/pubmed/30701050
http://dx.doi.org/10.4081/xeno.2016.6092