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Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model

Pancreatic cancer is a highly lethal disease in part due to incomplete tumor resection. Targeting by tumor-specific antibodies conjugated with a fluorescent label can result in selective labeling of cancer in vivo for surgical navigation. In the present study, we describe a patient-derived orthotopi...

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Detalles Bibliográficos
Autores principales: Lwin, Thinzar M., Miyake, Kentaro, Murakami, Takashi, DeLong, Jonathan C., Amirfakhri, Siamak, Filemoni, Filemoni, Yoon, Sang Nam, Yazaki, Paul J., Shivley, John E., Datnow, Brian, Clary, Bryan M., Hoffman, Robert M., Bouvet, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324662/
https://www.ncbi.nlm.nih.gov/pubmed/30647873
http://dx.doi.org/10.18632/oncotarget.26484