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Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model
Pancreatic cancer is a highly lethal disease in part due to incomplete tumor resection. Targeting by tumor-specific antibodies conjugated with a fluorescent label can result in selective labeling of cancer in vivo for surgical navigation. In the present study, we describe a patient-derived orthotopi...
Autores principales: | Lwin, Thinzar M., Miyake, Kentaro, Murakami, Takashi, DeLong, Jonathan C., Amirfakhri, Siamak, Filemoni, Filemoni, Yoon, Sang Nam, Yazaki, Paul J., Shivley, John E., Datnow, Brian, Clary, Bryan M., Hoffman, Robert M., Bouvet, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324662/ https://www.ncbi.nlm.nih.gov/pubmed/30647873 http://dx.doi.org/10.18632/oncotarget.26484 |
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