Detection of histone H3 K27M mutation and post-translational modifications in pediatric diffuse midline glioma via tissue immunohistochemistry informs diagnosis and clinical outcomes

Pediatric diffuse midline glioma is a highly morbid glial neoplasm that may arise in the thalamus or brainstem (also known as diffuse intrinsic pontine glioma or DIPG). Because tumor anatomic location precludes surgical resection, diagnosis and treatment is based on MR imaging and analysis of biopsy...

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Detalles Bibliográficos
Autores principales: Huang, Tina, Garcia, Roxanna, Qi, Jin, Lulla, Rishi, Horbinski, Craig, Behdad, Amir, Wadhwani, Nitin, Shilatifard, Ali, James, Charles, Saratsis, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324678/
https://www.ncbi.nlm.nih.gov/pubmed/30647848
http://dx.doi.org/10.18632/oncotarget.26430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324678/
https://www.ncbi.nlm.nih.gov/pubmed/30647848
http://dx.doi.org/10.18632/oncotarget.26430

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