KLHL5 knockdown increases cellular sensitivity to anticancer drugs

KLHL family genes are noted for their involvement in the E3 ligase ubiquitination pathway through binding with Cullin-3 (CUL3) resulting in degradation of specific binding partners. KLHLs are thus intriguing genes for cancer as they can directly influence the degradation of therapeutically relevant...

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Detalles Bibliográficos
Autores principales: Schleifer, Robert J., Li, Shuchun, Nechtman, Wyatt, Miller, Eric, Bai, Shan, Sharma, Ashok, She, Jin-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324770/
https://www.ncbi.nlm.nih.gov/pubmed/30647843
http://dx.doi.org/10.18632/oncotarget.26462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324770/
https://www.ncbi.nlm.nih.gov/pubmed/30647843
http://dx.doi.org/10.18632/oncotarget.26462

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