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KLHL5 knockdown increases cellular sensitivity to anticancer drugs
KLHL family genes are noted for their involvement in the E3 ligase ubiquitination pathway through binding with Cullin-3 (CUL3) resulting in degradation of specific binding partners. KLHLs are thus intriguing genes for cancer as they can directly influence the degradation of therapeutically relevant...
Autores principales: | Schleifer, Robert J., Li, Shuchun, Nechtman, Wyatt, Miller, Eric, Bai, Shan, Sharma, Ashok, She, Jin-Xiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324770/ https://www.ncbi.nlm.nih.gov/pubmed/30647843 http://dx.doi.org/10.18632/oncotarget.26462 |
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