Cargando…
In vivo assembly and large-scale purification of a GPCR - Gα fusion with Gβγ, and characterization of the active complex
G protein coupled receptors (GPCRs) are central players in recognizing a variety of stimuli to mediate diverse cellular responses. This myriad of functions is accomplished by their modular interactions with downstream intracellular transducers, such as heterotrimeric G proteins and arrestins. Assemb...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324789/ https://www.ncbi.nlm.nih.gov/pubmed/30620756 http://dx.doi.org/10.1371/journal.pone.0210131 |