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Evaluation of the analytical and diagnostic performance of a digital droplet polymerase chain reaction (ddPCR) assay to detect Trypanosoma cruzi DNA in blood samples

BACKGROUND: The recent development of novel Polymerase Chain Reaction (PCR) technologies that confer theoretical advantages over quantitative PCR has considerable potential in the diagnosis of low load infections, such as Trypanosoma cruzi in the chronic phase of Chagas disease. We evaluated the uti...

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Detalles Bibliográficos
Autores principales: Ramírez, Juan David, Herrera, Giovanny, Hernández, Carolina, Cruz-Saavedra, Lissa, Muñoz, Marina, Flórez, Carolina, Butcher, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324824/
https://www.ncbi.nlm.nih.gov/pubmed/30586355
http://dx.doi.org/10.1371/journal.pntd.0007063