Stem cells repurpose proliferation to contain a breach in their niche barrier

Adult stem cells are responsible for life-long tissue maintenance. They reside in and interact with specialized tissue microenvironments (niches). Using murine hair follicle as a model, we show that when junctional perturbations in the niche disrupt barrier function, adjacent stem cells dramatically...

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Detalles Bibliográficos
Autores principales: Lay, Kenneth, Yuan, Shaopeng, Gur-Cohen, Shiri, Miao, Yuxuan, Han, Tianxiao, Naik, Shruti, Pasolli, H Amalia, Larsen, Samantha B, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324878/
https://www.ncbi.nlm.nih.gov/pubmed/30520726
http://dx.doi.org/10.7554/eLife.41661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324878/
https://www.ncbi.nlm.nih.gov/pubmed/30520726
http://dx.doi.org/10.7554/eLife.41661

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