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Stem cells repurpose proliferation to contain a breach in their niche barrier
Adult stem cells are responsible for life-long tissue maintenance. They reside in and interact with specialized tissue microenvironments (niches). Using murine hair follicle as a model, we show that when junctional perturbations in the niche disrupt barrier function, adjacent stem cells dramatically...
Autores principales: | Lay, Kenneth, Yuan, Shaopeng, Gur-Cohen, Shiri, Miao, Yuxuan, Han, Tianxiao, Naik, Shruti, Pasolli, H Amalia, Larsen, Samantha B, Fuchs, Elaine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324878/ https://www.ncbi.nlm.nih.gov/pubmed/30520726 http://dx.doi.org/10.7554/eLife.41661 |
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