Cargando…

Redox Regulation of Mitochondrial Fission Protein Drp1 by Protein Disulfide Isomerase Limits Endothelial Senescence

Mitochondrial dynamics are tightly controlled by fusion and fission, and their dysregulation and excess reactive oxygen species (ROS) contribute to endothelial cell (EC) dysfunction. How redox signals regulate coupling between mitochondrial dynamics and endothelial (dys)function remains unknown. Her...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Young-Mee, Youn, Seock-Won, Sudhahar, Varadarajan, Das, Archita, Chandhri, Reyhaan, Grajal, Henar Cuervo, Kweon, Junghun, Leanhart, Silvia, He, Lianying, Toth, Peter T., Kitajewski, Jan, Rehman, Jalees, Yoon, Yisang, Cho, Jaehyung, Fukai, Tohru, Ushio-Fukai, Masuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324937/ https://www.ncbi.nlm.nih.gov/pubmed/29924999 http://dx.doi.org/10.1016/j.celrep.2018.05.054

Ejemplares similares

Endothelial Antioxidant-1: a Key Mediator of Copper-dependent Wound Healing in vivo
por: Das, Archita, et al.
Publicado: (2016)

Whole-Transcriptome Sequencing Analyses of Nuclear Antixoxidant-1 in Endothelial Cells: Role in Inflammation and Atherosclerosis
por: Sudhahar, Varadarajan, et al.
Publicado: (2022)

Copper Transport Protein Antioxidant-1 Promotes Inflammatory Neovascularization via Chaperone and Transcription Factor Function
por: Chen, Gin-Fu, et al.
Publicado: (2015)

The P-type ATPase transporter ATP7A promotes angiogenesis by limiting autophagic degradation of VEGFR2
por: Ash, Dipankar, et al.
Publicado: (2021)

Critical Role of Endothelial Hydrogen Peroxide in Post-Ischemic Neovascularization
por: Urao, Norifumi, et al.
Publicado: (2013)

Pentose Pathway Activation Is Superior to Increased Glycolysis for Therapeutic Angiogenesis in Peripheral Arterial Disease
por: Zaied, Abdelrahman A., et al.
Publicado: (2023)

Copper Transporter ATP7A Protects Against Endothelial Dysfunction in Type 1 Diabetic Mice by Regulating Extracellular Superoxide Dismutase
por: Sudhahar, Varadarajan, et al.
Publicado: (2013)

Modification of Cardiac Progenitor Cell-Derived Exosomes by miR-322 Provides Protection against Myocardial Infarction through Nox2-Dependent Angiogenesis
por: Youn, Seock-Won, et al.
Publicado: (2019)

Cross-Talk between NADPH Oxidase and Mitochondria: Role in ROS Signaling and Angiogenesis
por: Fukai, Tohru, et al.
Publicado: (2020)

Nuclear translocation of Atox1 potentiates activin A-induced cell migration and colony formation in colon cancer
por: Jana, Arundhati, et al.
Publicado: (2020)

Cysteine Oxidation of Copper transporter SLC31A1/CTR1, drives VEGFR2 signaling and Angiogenesis
por: Das, Archita, et al.
Publicado: (2022)

Editorial: Mitochondria, metabolism and cardiovascular diseases
por: Koga, Jun-ichiro, et al.
Publicado: (2022)

Protein disulfide isomerase in cardiovascular disease
por: Xiong, Bei, et al.
Publicado: (2020)

Flk1+ and VE-Cadherin+ Endothelial Cells Derived from iPSCs Recapitulates Vascular Development during Differentiation and Display Similar Angiogenic Potential as ESC-Derived Cells
por: Kohler, Erin E., et al.
Publicado: (2013)

Correction: Flk1+ and VE-Cadherin+ Endothelial Cells Derived from iPSCs Recapitulates Vascular Development during Differentiation and Display Similar Angiogenic Potential as ESC-Derived Cells
por: Kohler, Erin E., et al.
Publicado: (2014)

Shear and Integrin Outside-In Signaling Activate NADPH-Oxidase 2 to Promote Platelet Activation
por: Xu, Zheng, et al.
Publicado: (2021)

IQGAP1 Is Involved in Post-Ischemic Neovascularization by Regulating Angiogenesis and Macrophage Infiltration
por: Urao, Norifumi, et al.
Publicado: (2010)

Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1α
por: Tsang, Kit Man, et al.
Publicado: (2017)

Extracellular SOD-Derived H(2)O(2) Promotes VEGF Signaling in Caveolae/Lipid Rafts and Post-Ischemic Angiogenesis in Mice
por: Oshikawa, Jin, et al.
Publicado: (2010)

Adrenergic Regulation of Drp1-Driven Mitochondrial Fission in Cardiac Physio-Pathology
por: Jhun, Bong Sook, et al.
Publicado: (2018)

Nitroglycerin Tolerance in Caveolin-1 Deficient Mice
por: Mao, Mao, et al.
Publicado: (2014)

The role of conserved proteins DrpA and DrpB in nitrate respiration of Thermus thermophilus
por: Chahlafi, Zahra, et al.
Publicado: (2018)

Combined deficiency of Notch1 and Notch3 causes pericyte dysfunction, models CADASIL, and results in arteriovenous malformations
por: Kofler, Natalie M., et al.
Publicado: (2015)

Embracing Diversity, Equity, and Inclusion in the Scientific Community—Viewpoints of the Diversity, Equity, and Inclusion Committee of the North American Vascular Biology Organization
por: Garelnabi, Mahdi, et al.
Publicado: (2022)

CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation
por: Xu, Shangcheng, et al.
Publicado: (2016)

The flexibility and dynamics of protein disulfide isomerase
por: Römer, Rudolf A., et al.
Publicado: (2016)

Renin-Angiotensin Activation and Oxidative Stress in Early Heart Failure with Preserved Ejection Fraction
por: Negi, Smita I., et al.
Publicado: (2015)

Binding of Host Cell Surface Protein Disulfide Isomerase by Anaplasma phagocytophilum Asp14 Enables Pathogen Infection
por: Green, Ryan S., et al.
Publicado: (2020)

The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration
por: Perri, Emma R., et al.
Publicado: (2016)

Functional Differences in Yeast Protein Disulfide Isomerases
por: Nørgaard, Per, et al.
Publicado: (2001)

Protein Disulfide Isomerase and Host-Pathogen Interaction
por: Stolf, Beatriz S., et al.
Publicado: (2011)

Compact Conformations of Human Protein Disulfide Isomerase
por: Yang, Shang, et al.
Publicado: (2014)

The human protein disulfide isomerase gene family
por: Galligan, James J, et al.
Publicado: (2012)

Emerging roles of protein disulfide isomerase in cancer
por: Lee, Eunyoug, et al.
Publicado: (2017)

Roles of Protein Disulfide Isomerase in Breast Cancer
por: Yang, Suhui, et al.
Publicado: (2022)

DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis
por: Milani, Mateus, et al.
Publicado: (2017)

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins
por: Hoffstrom, Benjamin G., et al.
Publicado: (2010)

Protein disulfide isomerase a multifunctional protein with multiple physiological roles
por: Ali Khan, Hyder, et al.
Publicado: (2014)

Protein Disulfide Isomerase Interacts with Tau Protein and Inhibits Its Fibrillization
por: Xu, Li-Rong, et al.
Publicado: (2013)

Expression and characterization of protein disulfide isomerase family proteins in bread wheat
por: Kimura, Shizuka, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_a1gsm6h2hlqsnh0hhchfjnef8c