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Insulin signaling in Drosophila melanogaster mediates Aβ toxicity
Alzheimer’s disease (AD) and diabetes are clinically positively correlated. However, the connection between them is not clarified. Here, using Drosophila as a model system, we show that reducing insulin signaling can effectively suppress the toxicity from Aβ (Amyloid beta 42) expression. On the othe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325060/ https://www.ncbi.nlm.nih.gov/pubmed/30652125 http://dx.doi.org/10.1038/s42003-018-0253-x |