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TRPC6 inactivation does not affect loss of renal function in nephrotoxic serum glomerulonephritis in rats, but reduces severity of glomerular lesions

Canonical transient receptor potential-6 (TRPC6) channels have been implicated in a variety of chronic kidney diseases including familial and acquired forms of focal and segmental glomerulosclerosis (FSGS) and renal fibrosis following ureteral obstruction. Here we have examined the role of TRPC6 in...

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Detalles Bibliográficos
Autores principales: Kim, Eun Young, Shotorbani, Parisa Yazdizadeh, Dryer, Stuart E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325086/
https://www.ncbi.nlm.nih.gov/pubmed/30662960
http://dx.doi.org/10.1016/j.bbrep.2018.12.006