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Teaching an old dog new tricks: next-generation CAR T cells

Adoptive T cell therapy (ACT) refers to the therapeutic use of T cells. T cells genetically engineered to express chimeric antigen receptors (CAR) constitute the most clinically advanced form of ACT approved to date for the treatment of CD19-positive leukaemias and lymphomas. CARs are synthetic rece...

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Detalles Bibliográficos
Autores principales: Tokarew, Nicholas, Ogonek, Justyna, Endres, Stefan, von Bergwelt-Baildon, Michael, Kobold, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325111/
https://www.ncbi.nlm.nih.gov/pubmed/30413825
http://dx.doi.org/10.1038/s41416-018-0325-1