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Teaching an old dog new tricks: next-generation CAR T cells

Adoptive T cell therapy (ACT) refers to the therapeutic use of T cells. T cells genetically engineered to express chimeric antigen receptors (CAR) constitute the most clinically advanced form of ACT approved to date for the treatment of CD19-positive leukaemias and lymphomas. CARs are synthetic rece...

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Detalles Bibliográficos
Autores principales:	Tokarew, Nicholas, Ogonek, Justyna, Endres, Stefan, von Bergwelt-Baildon, Michael, Kobold, Sebastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325111/ https://www.ncbi.nlm.nih.gov/pubmed/30413825 http://dx.doi.org/10.1038/s41416-018-0325-1

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