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Role of the P2X7 receptor in inflammation-mediated changes in the osteogenesis of periodontal ligament stem cells

Accumulating evidence indicates that the pluripotency of periodontal ligament stem cells (PDLSCs) is compromised under inflammatory conditions; however, the underlying mechanisms remain largely unexplored. In this study, we hypothesize that the P2X7 receptor (P2X7R) is a key molecule linked to infla...

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Detalles Bibliográficos
Autores principales: Xu, Xin-Yue, He, Xiao-Tao, Wang, Jia, Li, Xuan, Xia, Yu, Tan, Yi-Zhou, Chen, Fa-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325129/
https://www.ncbi.nlm.nih.gov/pubmed/30622236
http://dx.doi.org/10.1038/s41419-018-1253-y