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Wnt3a disrupts GR-TEAD4-PPARγ2 positive circuits and cytoskeletal rearrangement in a β-catenin-dependent manner during early adipogenesis

Adipogenesis is a process which induces or represses many genes in a way to drive irreversible changes of cell phenotypes; lipid accumulation, round cell-shape, secreting many adipokines. As a master transcription factor (TF), PPARγ2 induces several target genes to orchestrate these adipogenic chang...

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Detalles Bibliográficos
Autores principales: Park, Bongju, Chang, Soojeong, Lee, Gwan-Jun, Kang, Byeongsoo, Kim, Jong Kyoung, Park, Hyunsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325140/
https://www.ncbi.nlm.nih.gov/pubmed/30622240
http://dx.doi.org/10.1038/s41419-018-1249-7