Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability

Thrombospondins (Thbs) are a family of five secreted matricellular glycoproteins in vertebrates that broadly affect cell-matrix interaction. While Thbs4 is known to protect striated muscle from disease by enhancing sarcolemmal stability through increased integrin and dystroglycan attachment complexe...

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Detalles Bibliográficos
Autores principales: Schips, Tobias G., Vanhoutte, Davy, Vo, Alexander, Correll, Robert N., Brody, Matthew J., Khalil, Hadi, Karch, Jason, Tjondrokoesoemo, Andoria, Sargent, Michelle A., Maillet, Marjorie, Ross, Robert S., Molkentin, Jeffery D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325143/
https://www.ncbi.nlm.nih.gov/pubmed/30622267
http://dx.doi.org/10.1038/s41467-018-08026-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325143/
https://www.ncbi.nlm.nih.gov/pubmed/30622267
http://dx.doi.org/10.1038/s41467-018-08026-8

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