VISTA expressed in tumour cells regulates T cell function

BACKGROUND: V-domain Ig suppressor of T cell activation (VISTA) is a novel inhibitory immune-checkpoint protein. VISTA expression on tumour cells and the associated regulatory mechanisms remain unclear. We investigated VISTA expression and function in tumour cells, and evaluated its mechanism and ac...

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Detalles Bibliográficos
Autores principales: Mulati, Kumuluzi, Hamanishi, Junzo, Matsumura, Noriomi, Chamoto, Kenji, Mise, Nathan, Abiko, Kaoru, Baba, Tsukasa, Yamaguchi, Ken, Horikawa, Naoki, Murakami, Ryusuke, Taki, Mana, Budiman, Kharma, Zeng, Xiang, Hosoe, Yuko, Azuma, Miyuki, Konishi, Ikuo, Mandai, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325144/
https://www.ncbi.nlm.nih.gov/pubmed/30382166
http://dx.doi.org/10.1038/s41416-018-0313-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325144/
https://www.ncbi.nlm.nih.gov/pubmed/30382166
http://dx.doi.org/10.1038/s41416-018-0313-5

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