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On chaotic dynamics in transcription factors and the associated effects in differential gene regulation

The control of proteins by a transcription factor with periodically varying concentration exhibits intriguing dynamical behaviour. Even though it is accepted that transcription factors vary their dynamics in response to different situations, insight into how this affects downstream genes is lacking....

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Detalles Bibliográficos
Autores principales: Heltberg, Mathias L., Krishna, Sandeep, Jensen, Mogens H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325146/
https://www.ncbi.nlm.nih.gov/pubmed/30622249
http://dx.doi.org/10.1038/s41467-018-07932-1