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Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer

BACKGROUND: Immune infiltration is implicated in the development of acquired resistance to anti-angiogenic cancer therapy. We therefore investigated the correlation between neutrophil infiltration in metastasis of colorectal cancer (CRC) patients and survival after treatment with bevacizumab. Our st...

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Detalles Bibliográficos
Autores principales: Schiffmann, Lars Mortimer, Fritsch, Melanie, Gebauer, Florian, Günther, Saskia Diana, Stair, Neil Richard, Seeger, Jens Michael, Thangarajah, Fabinshy, Dieplinger, Georg, Bludau, Marc, Alakus, Hakan, Göbel, Heike, Quaas, Alexander, Zander, Thomas, Hilberg, Frank, Bruns, Christiane Josephine, Kashkar, Hamid, Coutelle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325148/
https://www.ncbi.nlm.nih.gov/pubmed/30377339
http://dx.doi.org/10.1038/s41416-018-0198-3