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PD-Loma: a cancer entity with a shared sensitivity to the PD-1/PD-L1 pathway blockade

Clinical trials have now identified over 30 cancer histotypes with sensitivity to anti-PD-(L)1 therapies. It is the first time in oncology that a class of drugs has demonstrated such a wide spectrum of activity in monotherapy. This subgroup of cancers (‘PD-Lomas’) is driving the clinical research st...

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Detalles Bibliográficos
Autores principales: Hirsch, Laure, Zitvogel, Laurence, Eggermont, Alexander, Marabelle, Aurelien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325162/
https://www.ncbi.nlm.nih.gov/pubmed/30413824
http://dx.doi.org/10.1038/s41416-018-0294-4