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Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers

Mass spectrometry-based lipidomics is the primary tool for the structural analysis of lipids but the effective localization of carbon–carbon double bonds (C=C) in unsaturated lipids to distinguish C=C location isomers remains challenging. Here, we develop a large-scale lipid analysis platform by cou...

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Detalles Bibliográficos
Autores principales: Zhang, Wenpeng, Zhang, Donghui, Chen, Qinhua, Wu, Junhan, Ouyang, Zheng, Xia, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325166/
https://www.ncbi.nlm.nih.gov/pubmed/30622271
http://dx.doi.org/10.1038/s41467-018-07963-8