Two Point Mutations in Old World Hantavirus Glycoproteins Afford the Generation of Highly Infectious Recombinant Vesicular Stomatitis Virus Vectors

Rodent-to-human transmission of hantaviruses is associated with severe disease. Currently, no FDA-approved, specific antivirals or vaccines are available, and the requirement for high biocontainment (biosafety level 3 [BSL-3]) laboratories limits hantavirus research. To study hantavirus entry in a B...

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Detalles Bibliográficos
Autores principales: Slough, Megan M., Chandran, Kartik, Jangra, Rohit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325249/
https://www.ncbi.nlm.nih.gov/pubmed/30622188
http://dx.doi.org/10.1128/mBio.02372-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325249/
https://www.ncbi.nlm.nih.gov/pubmed/30622188
http://dx.doi.org/10.1128/mBio.02372-18

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