Paricalcitol attenuates indoxyl sulfate-induced apoptosis through the inhibition of MAPK, Akt, and NF-kB activation in HK-2 cells

BACKGROUND/AIMS: Indoxyl sulfate (IS) is a uremic toxin and an important causative factor in the progression of chronic kidney disease. Recently, paricalcitol (19-nor-1,25-dihydroxyvitamin D2) was shown to exhibit protective effects in kidney injury. Here, we investigated the effects of paricalcitol...

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Detalles Bibliográficos
Autores principales: Park, Jung Sun, Choi, Hoon In, Bae, Eun Hui, Ma, Seong Kwon, Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325450/
https://www.ncbi.nlm.nih.gov/pubmed/28992684
http://dx.doi.org/10.3904/kjim.2016.298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325450/
https://www.ncbi.nlm.nih.gov/pubmed/28992684
http://dx.doi.org/10.3904/kjim.2016.298

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