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Adenosine Signaling through A1 Receptors Inhibits Chemosensitive Neurons in the Retrotrapezoid Nucleus

A subset of neurons in the retrotrapezoid nucleus (RTN) function as respiratory chemoreceptors by regulating depth and frequency of breathing in response to changes in tissue CO(2)/H(+). The activity of chemosensitive RTN neurons is also subject to modulation by CO(2)/H(+)-dependent purinergic signa...

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Detalles Bibliográficos
Autores principales: James, S. D., Hawkins, V. E., Falquetto, B., Ruskin, D. N., Masino, S. A., Moreira, T. S., Olsen, M. L., Mulkey, D. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325544/
https://www.ncbi.nlm.nih.gov/pubmed/30627640
http://dx.doi.org/10.1523/ENEURO.0404-18.2018