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Ovarian Cycle Stages Modulate Alzheimer-Related Cognitive and Brain Network Alterations in Female Mice

Alzheimer’s disease (AD) begins several decades before the onset of clinical symptoms, at a time when women may still undergo reproductive cycling. Whether ovarian functions alter substrates of AD pathogenesis is unknown. Here we show that ovarian cycle stages significantly modulate AD-related alter...

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Detalles Bibliográficos
Autores principales: Broestl, Lauren, Worden, Kurtresha, Moreno, Arturo J., Davis, Emily J., Wang, Dan, Garay, Bayardo, Singh, Tanya, Verret, Laure, Palop, Jorge J., Dubal, Dena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325547/
https://www.ncbi.nlm.nih.gov/pubmed/30627643
http://dx.doi.org/10.1523/ENEURO.0132-17.2018