Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing

Menthol contributes to poor cessation rates among smokers, in part because menthol enhances nicotine reward and reinforcement. Mentholated tobacco products contain (−)-menthol and (+)-menthol, in varying proportions. We examined these two menthol stereoisomers for their ability to upregulate α4β2 nA...

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Detalles Bibliográficos
Autores principales: Henderson, Brandon J., Grant, Stephen, Chu, Betty W., Shahoei, Rezvan, Huard, Stephanie M., Saladi, Shyam S. M., Tajkhorshid, Emad, Dougherty, Dennis A., Lester, Henry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325563/
https://www.ncbi.nlm.nih.gov/pubmed/30627659
http://dx.doi.org/10.1523/ENEURO.0465-18.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325563/
https://www.ncbi.nlm.nih.gov/pubmed/30627659
http://dx.doi.org/10.1523/ENEURO.0465-18.2018

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