Coprs inactivation leads to a derepression of LINE1 transposons in spermatocytes

Repression of retrotransposons is essential for genome integrity during germ cell development and is tightly controlled through epigenetic mechanisms. In primordial germ cells, protein arginine N‐methyltransferase (Prmt5) is involved in retrotransposon repression by methylating Piwi proteins, which...

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Detalles Bibliográficos
Autores principales: Paul, Conception, Delpech, Hélène, Haouzi, Delphine, Hamamah, Samir, Sardet, Claude, Fabbrizio, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325579/
https://www.ncbi.nlm.nih.gov/pubmed/30652083
http://dx.doi.org/10.1002/2211-5463.12562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325579/
https://www.ncbi.nlm.nih.gov/pubmed/30652083
http://dx.doi.org/10.1002/2211-5463.12562

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