Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo

CRISPR/dCas9 systems can precisely control endogenous gene expression without interrupting host genomic sequence and have provided a novel and feasible strategy for the treatment of cancers at the transcriptional level. However, development of CRISPR/dCas9‐based anti‐cancer therapeutics remains chal...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Zhao, Kai, Wang, Chun, Zhang, Zhanzhan, Zheng, Chunxiong, Zhao, Yu, Zheng, Yadan, Liu, Chaoyong, An, Yingli, Shi, Linqi, Kang, Chunsheng, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325604/
https://www.ncbi.nlm.nih.gov/pubmed/30643726
http://dx.doi.org/10.1002/advs.201801423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325604/
https://www.ncbi.nlm.nih.gov/pubmed/30643726
http://dx.doi.org/10.1002/advs.201801423

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