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Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo

CRISPR/dCas9 systems can precisely control endogenous gene expression without interrupting host genomic sequence and have provided a novel and feasible strategy for the treatment of cancers at the transcriptional level. However, development of CRISPR/dCas9‐based anti‐cancer therapeutics remains chal...

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Detalles Bibliográficos
Autores principales:	Liu, Qi, Zhao, Kai, Wang, Chun, Zhang, Zhanzhan, Zheng, Chunxiong, Zhao, Yu, Zheng, Yadan, Liu, Chaoyong, An, Yingli, Shi, Linqi, Kang, Chunsheng, Liu, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325604/ https://www.ncbi.nlm.nih.gov/pubmed/30643726 http://dx.doi.org/10.1002/advs.201801423

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