Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial

Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and experimental data suggest that copper may increase its anti-neoplastic propert...

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Detalles Bibliográficos
Autores principales: Jakola, Asgeir Store, Werlenius, Katja, Mudaisi, Munila, Hylin, Sofia, Kinhult, Sara, Bartek, Jiri, Salvesen, Øyvind, Carlsen, Sven Magnus, Strandéus, Michael, Lindskog, Magnus, Löfgren, David, Rydenhag, Bertil, Carstam, Louise, Gulati, Sasha, Solheim, Ole, Solheim, Tora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325620/
https://www.ncbi.nlm.nih.gov/pubmed/30647912
http://dx.doi.org/10.12688/f1000research.16786.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325620/
https://www.ncbi.nlm.nih.gov/pubmed/30647912
http://dx.doi.org/10.12688/f1000research.16786.1

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