3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing

Parkinson's disease (PD)‐specific neurons, grown in standard 2D cultures, typically only display weak endophenotypes. The cultivation of PD patient‐specific neurons, derived from induced pluripotent stem cells carrying the LRRK2‐G2019S mutation, is optimized in 3D microfluidics. The automated i...

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Detalles Bibliográficos
Autores principales: Bolognin, Silvia, Fossépré, Marie, Qing, Xiaobing, Jarazo, Javier, Ščančar, Janez, Moreno, Edinson Lucumi, Nickels, Sarah L., Wasner, Kobi, Ouzren, Nassima, Walter, Jonas, Grünewald, Anne, Glaab, Enrico, Salamanca, Luis, Fleming, Ronan M. T., Antony, Paul M. A., Schwamborn, Jens C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325628/
https://www.ncbi.nlm.nih.gov/pubmed/30643711
http://dx.doi.org/10.1002/advs.201800927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325628/
https://www.ncbi.nlm.nih.gov/pubmed/30643711
http://dx.doi.org/10.1002/advs.201800927

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