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The C677T Polymorphism of the Methylenetetrahydrofolate Reductase Gene and Susceptibility to Late-onset Alzheimer’s Disease

Folate metabolism makes a crucial contribution towards late-onset Alzheimer’s disease (LOAD). Moreover, methylenetetrahydrofolate reductase (MTHFR) constitutes the primary enzyme of the folate pathway. We hypothesize that there is an association of C677T polymorphism in the MTHFR gene with the susce...

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Detalles Bibliográficos
Autores principales: Yi, Jian, Xiao, Lan, Zhou, Sheng-Qiang, Zhang, Wen-Jiang, Liu, Bai-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325648/
https://www.ncbi.nlm.nih.gov/pubmed/30631824
http://dx.doi.org/10.1515/med-2019-0006