Evaluation of strategies for the assembly of diverse bacterial genomes using MinION long-read sequencing

BACKGROUND: Short-read sequencing technologies have made microbial genome sequencing cheap and accessible. However, closing genomes is often costly and assembling short reads from genomes that are repetitive and/or have extreme %GC content remains challenging. Long-read, single-molecule sequencing t...

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Detalles Bibliográficos
Autores principales: Goldstein, Sarah, Beka, Lidia, Graf, Joerg, Klassen, Jonathan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325685/
https://www.ncbi.nlm.nih.gov/pubmed/30626323
http://dx.doi.org/10.1186/s12864-018-5381-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325685/
https://www.ncbi.nlm.nih.gov/pubmed/30626323
http://dx.doi.org/10.1186/s12864-018-5381-7

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