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Overexpression of CD59 inhibits apoptosis of T-acute lymphoblastic leukemia via AKT/Notch1 signaling pathway

BACKGROUND: T-acute lymphoblastic leukemia (T-ALL) was a hematological malignancy characterized by the accumulation of immature T cells in bone marrow and peripheral blood. In this study, we tried to explore the physiological role of CD59 in T-ALL. METHODS: In this study, we collected the bone marro...

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Detalles Bibliográficos
Autores principales: Jia, Yanfei, Qi, Yan, Wang, Yunshan, Ma, Xiaoli, Xu, Yihui, Wang, Jun, Zhang, Xiaoqian, Gao, Meihua, Cong, Beibei, Han, Shuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325688/
https://www.ncbi.nlm.nih.gov/pubmed/30636930
http://dx.doi.org/10.1186/s12935-018-0714-9